Endocrine Abstracts

Introduction: Hypercortisolism is considered to be a rare condition with an estimated incidence between 0.4 and 2.4 cases per million per year, typically manifests as the clinically and biochemically evident Cushing’s syndrome. However, a more subtle form, known as subclinical hypercortisolism (SH) or autonomous cortisol secretion (ACS), poses diagnostic challenges. It is defined as excessive cortisol secretion without the classic manifestations of clinically overt Cushin...

Introduction and importance: Pseudo-Cushing’s syndrome (PCS) encompasses a spectrum of medical conditions, both physiological and non-physiological, that replicate the clinical features of Cushing’s syndrome (CS). In PCS, there is a presence of mild biochemical hypercortisolaemia, which is carefully regulated by physiological feedback hormonal control mechanisms. Physiological conditions contributing to PCS include factors like pregnancy surgical or emotional stress,...